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Human secretin

Secretin

CAS: 1393-25-5;17034-35-4

Molecular Formula: C130H220N44O40

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Human secretin - Names and Identifiers

Name Secretin
Synonyms Vitrum
C13523
Secretin
Secreflo
Secrepan
Secretine
Secretina
SecreFlow
secretolin
Secretolin
Secretinum
Secretin-Kabi
Secretin human
Human secretin
Secretin, Human
UNII-88C55N56UU
Secretin-ferring
Secretin (porcine)
Secretine [INN-French]
Secretinum [INN-Latin]
Secretina [INN-Spanish]
HSDGTFTSELSRLREGARLQRLLQGLV-NH3
HSDGTFTSELSRLREGARLQRLLQGLV-NH2
Secretin (porcine), 15-L-glutamic acid-16-glycine-
Hormone of the duodenal mucosa that activates pancreatic secretion and lowers the blood sugar level
HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2
H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2
HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2 HUMAN
L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
L-Histidyl-L-seryl-L-alpha-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-alpha-aspartyl-L-seryl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide
CAS 1393-25-5
17034-35-4
EINECS 215-733-3

Human secretin - Physico-chemical Properties

Molecular FormulaC130H220N44O40
Molar Mass3039.41
Appearancepowder
Storage Condition−20°C
MDLMFCD00133810
Physical and Chemical PropertiesStorage Conditions:? 20℃
WGK Germany:3

Human secretin - Risk and Safety

WGK Germany3

Human secretin - Nature

Open Data Verified Data

is a digestive tract hormone produced by the duodenum and the upper jejunum, secreted by the S cells, soluble in water, molecular weight 3056. Mainly by the kidney clearance, Half-Life is short, 2. 39min. The main factor promoting the release of secretin is gastric acid, and the pH in the duodenum or jejunum is <4.5.
Stimulates the release of secretin. The secretion of secretin is also increased after a meal. Somatostatin and enkephalin can inhibit the release. This product is a linear 27 peptide. It stimulates pancreatic acinar cells to secrete water and bicarbonate. Alkalization of the duodenum facilitates enzyme reaction, inhibits gastric acid secretion and stimulates insulin secretion; It enhances cholecystokinin (CCK) secretagogue; Inhibits postprandial gastrin secretion, and reduces gastric acid, stimulate the secretion of pepsin, inhibit pentagastrin to stimulate the secretion of human gastric acid; And promote bile excretion; Inhibit the contraction of gastrointestinal smooth muscle, reduce the tension of lower esophageal sphincter, but increase the tension of pyloric sphincter, inhibits gastric emptying, increases the effect of CCK on the contraction of the gallbladder.

Last Update:2024-01-02 23:10:35

Human secretin - Application

Open Data Verified Data
  • is used in combination with cholecystokinin for the diagnosis of pancreatic diseases; It is also used to cooperate with pancreatic vascular and retroperitoneal gas injection and other imaging, to increase the clarity of vascular imaging and shorten the time of arterial filling, to aid in the diagnosis of a pancreatic tumor or cyst. In addition, it is also used to treat duodenal ulcer, but the action time is too short, and the dose is large.
  • usage and dose of ulcer, 50~100 units per day; Intravenous injection of p-s test, 1 ~ 2u/kg body weight, 5 min after the injection of cholecystokinin. Skin test should be performed before use.
  • preparation: 100 units/bottle; 75 clinical units/vial (1 Clinical Unit = 4 units).
Last Update:2025-08-19 16:24:40

Human secretin - Safety

Open Data Verified Data

occasional allergic reaction. High dose visible Diarrhea. Acute pancreatitis, allergic asthma and allergic history of patients with caution.

Last Update:2022-01-01 11:11:43
Human secretin
Supplier List
Shanghai Macklin Biochemical Co., Ltd
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Product Name: Secretin porcine Visit Supplier Webpage Request for quotation
CAS: 17034-35-4
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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MedChemExpress (MCE)
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Product Name: Secretin (swine) Visit Supplier Webpage Request for quotation
CAS: 17034-35-4
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SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Secretin Acetate Visit Supplier Webpage Request for quotation
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Secretin porcine Visit Supplier Webpage Request for quotation
CAS: 17034-35-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Secretin porcine Visit Supplier Webpage Request for quotation
CAS: 17034-35-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Secretin,porcine Request for quotation
CAS: 17034-35-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Secretin porcine Visit Supplier Webpage Request for quotation
CAS: 17034-35-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
Multiple SpecificationsSpot supply
Product Name: Secretin (swine) Visit Supplier Webpage Request for quotation
CAS: 17034-35-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Secretin Acetate Visit Supplier Webpage Request for quotation
CAS: 17034-35-4
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Secretin porcine Visit Supplier Webpage Request for quotation
CAS: 17034-35-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
View History
Human secretin
Acetaldehyde di methyl acetel
F 6060
6-PENTADECYLSALICYLIC ACID
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